F3S (p.Phe3Ser) variant of CD2 (T-cell surface antigen CD2)
F3S (p.Phe3Ser) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
F3S (p.Phe3Ser) variant details
- p.Phe3Ser
- gnomAD 1-116754500-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.20
- MetaLR 0.18
- MetaSVM -0.86
- CADD 18.40
- PolyPhen-2 0.21
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available