E76K (p.Glu76Lys) variant of CD2 (T-cell surface antigen CD2)
E76K (p.Glu76Lys) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
E76K (p.Glu76Lys) variant details
- p.Glu76Lys
- gnomAD 1-116754795-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0974
- REVEL 0.08
- MetaLR 0.03
- MetaSVM -1.09
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.97
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available