E60G (p.Glu60Gly) variant of CD2 (T-cell surface antigen CD2)
E60G (p.Glu60Gly) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
E60G (p.Glu60Gly) variant details
- p.Glu60Gly
- ExAC rs779582184
- gnomAD rs779582184
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.15
- MetaLR 0.13
- MetaSVM -0.91
- CADD 13.20
- PolyPhen-2 0.64
- SIFT 0.24
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available