D56N (p.Asp56Asn) variant of CD2 (T-cell surface antigen CD2)
D56N (p.Asp56Asn) in CD2 (T-cell surface antigen CD2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
D56N (p.Asp56Asn) variant details
- p.Asp56Asn
- rs1024165793
- NCI-TCGA Cosmic COSV6564
- cosmic curated COSV65643
- TOPMed rs1024165793
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.13
- MetaLR 0.24
- MetaSVM -0.78
- CADD 15.60
- PolyPhen-2 0.93
- SIFT 0.06
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available