C5Y (p.Cys5Tyr) variant of CD2 (T-cell surface antigen CD2)
C5Y (p.Cys5Tyr) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
C5Y (p.Cys5Tyr) variant details
- p.Cys5Tyr
- TOPMed rs989279218
- Missense
- Variant Prioritization Score for Impact Estimate 0.175
- REVEL 0.16
- MetaLR 0.21
- MetaSVM -0.87
- CADD 7.07
- SIFT 0.44
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available