C5F (p.Cys5Phe) variant of CD2 (T-cell surface antigen CD2)
C5F (p.Cys5Phe) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
C5F (p.Cys5Phe) variant details
- p.Cys5Phe
- gnomAD 1-116754506-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.33
- MetaLR 0.39
- MetaSVM -0.59
- CADD 14.20
- PolyPhen-2 0.27
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available