A36D (p.Ala36Asp) variant of CD2 (T-cell surface antigen CD2)
A36D (p.Ala36Asp) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
A36D (p.Ala36Asp) variant details
- p.Ala36Asp
- gnomAD 1-116754676-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.17
- MetaLR 0.15
- MetaSVM -0.67
- CADD 9.58
- PolyPhen-2 0.95
- SIFT 0.02
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available