T42I (p.Thr42Ile) variant of CD19 (B-lymphocyte antigen CD19)
T42I (p.Thr42Ile) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
T42I (p.Thr42Ile) variant details
- p.Thr42Ile
- TOPMed rs1174480734
- gnomAD rs1174480734
- Missense
- Variant Prioritization Score for Impact Estimate 0.164
- REVEL 0.06
- MetaLR 0.02
- MetaSVM -1.00
- CADD 13.60
- PolyPhen-2 0.06
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available