S53C (p.Ser53Cys) variant of CD19 (B-lymphocyte antigen CD19)
S53C (p.Ser53Cys) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
S53C (p.Ser53Cys) variant details
- p.Ser53Cys
- ExAC rs750625293
- TOPMed rs750625293
- gnomAD rs750625293
- Missense
- Variant Prioritization Score for Impact Estimate 0.0591
- REVEL 0.02
- MetaLR 0.01
- MetaSVM -1.00
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.09
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available