R54Q (p.Arg54Gln) variant of CD19 (B-lymphocyte antigen CD19)
R54Q (p.Arg54Gln) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
R54Q (p.Arg54Gln) variant details
- p.Arg54Gln
- ESP rs150438147
- ExAC rs150438147
- TOPMed rs150438147
- gnomAD rs150438147
- Missense
- Variant Prioritization Score for Impact Estimate 0.117
- REVEL 0.10
- MetaLR 0.02
- MetaSVM -1.00
- CADD 5.68
- PolyPhen-2 0.01
- SIFT 0.35
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available