P2L (p.Pro2Leu) variant of CD19 (B-lymphocyte antigen CD19)
P2L (p.Pro2Leu) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
P2L (p.Pro2Leu) variant details
- p.Pro2Leu
- ExAC rs766808956
- gnomAD rs766808956
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.09
- MetaLR 0.11
- MetaSVM -0.95
- CADD 13.40
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available