P20A (p.Pro20Ala) variant of CD19 (B-lymphocyte antigen CD19)
P20A (p.Pro20Ala) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
P20A (p.Pro20Ala) variant details
- p.Pro20Ala
- TOPMed rs1028550245
- gnomAD rs1028550245
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.05
- MetaLR 0.06
- MetaSVM -1.06
- CADD 6.58
- PolyPhen-2 0.13
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available