L68M (p.Leu68Met) variant of CD19 (B-lymphocyte antigen CD19)
L68M (p.Leu68Met) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
L68M (p.Leu68Met) variant details
- p.Leu68Met
- Ensembl rs1964663388
- Missense
- Variant Prioritization Score for Impact Estimate 0.0984
- REVEL 0.07
- MetaLR 0.09
- MetaSVM -0.86
- CADD 0.41
- PolyPhen-2 0.69
- SIFT 0.10
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available