L66P (p.Leu66Pro) variant of CD19 (B-lymphocyte antigen CD19)
L66P (p.Leu66Pro) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
L66P (p.Leu66Pro) variant details
- p.Leu66Pro
- gnomAD rs1964663290
- Missense
- Variant Prioritization Score for Impact Estimate 0.0767
- REVEL 0.03
- MetaLR 0.06
- MetaSVM -1.05
- CADD 3.29
- SIFT 0.17
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available