L66M (p.Leu66Met) variant of CD19 (B-lymphocyte antigen CD19)
L66M (p.Leu66Met) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
L66M (p.Leu66Met) variant details
- p.Leu66Met
- Ensembl rs2152228244
- Missense
- Variant Prioritization Score for Impact Estimate 0.102
- REVEL 0.04
- MetaLR 0.10
- MetaSVM -1.04
- CADD 8.39
- PolyPhen-2 0.69
- SIFT 0.14
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available