L58I (p.Leu58Ile) variant of CD19 (B-lymphocyte antigen CD19)
L58I (p.Leu58Ile) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
L58I (p.Leu58Ile) variant details
- p.Leu58Ile
- gnomAD rs1289103595
- Missense
- Variant Prioritization Score for Impact Estimate 0.07
- REVEL 0.03
- MetaLR 0.06
- MetaSVM -1.07
- CADD 0.00
- PolyPhen-2 0.04
- SIFT 0.19
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available