L39V (p.Leu39Val) variant of CD19 (B-lymphocyte antigen CD19)
L39V (p.Leu39Val) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
L39V (p.Leu39Val) variant details
- p.Leu39Val
- gnomAD 16-28932372-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.13
- CADD 21.00
- PolyPhen-2 0.61
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- Literature evidence available