L39F (p.Leu39Phe) variant of CD19 (B-lymphocyte antigen CD19)
L39F (p.Leu39Phe) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
L39F (p.Leu39Phe) variant details
- p.Leu39Phe
- gnomAD rs1434266587
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.07
- MetaLR 0.02
- MetaSVM -1.05
- CADD 14.70
- PolyPhen-2 0.10
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available