K59T (p.Lys59Thr) variant of CD19 (B-lymphocyte antigen CD19)
K59T (p.Lys59Thr) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
K59T (p.Lys59Thr) variant details
- p.Lys59Thr
- TOPMed rs1453893043
- gnomAD rs1453893043
- Missense
- Variant Prioritization Score for Impact Estimate 0.069
- REVEL 0.03
- MetaLR 0.03
- MetaSVM -1.05
- CADD 0.04
- PolyPhen-2 0.00
- SIFT 0.61
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available