K27R (p.Lys27Arg) variant of CD19 (B-lymphocyte antigen CD19)
K27R (p.Lys27Arg) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
K27R (p.Lys27Arg) variant details
- p.Lys27Arg
- cosmic curated COSV61188
- ExAC rs763492717
- TOPMed rs763492717
- gnomAD rs763492717
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.04
- MetaLR 0.02
- MetaSVM -0.99
- CADD 23.40
- PolyPhen-2 0.13
- SIFT 0.01
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available