H74Y (p.His74Tyr) variant of CD19 (B-lymphocyte antigen CD19)
H74Y (p.His74Tyr) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
H74Y (p.His74Tyr) variant details
- p.His74Tyr
- gnomAD 16-28932477-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.10
- CADD 3.49
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available