H74R (p.His74Arg) variant of CD19 (B-lymphocyte antigen CD19)
H74R (p.His74Arg) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
H74R (p.His74Arg) variant details
- p.His74Arg
- gnomAD rs1327207135
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- REVEL 0.10
- MetaLR 0.06
- MetaSVM -1.01
- CADD 1.53
- PolyPhen-2 0.00
- SIFT 0.22
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available