F85L (p.Phe85Leu) variant of CD19 (B-lymphocyte antigen CD19)
F85L (p.Phe85Leu) in CD19 (B-lymphocyte antigen CD19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
F85L (p.Phe85Leu) variant details
- p.Phe85Leu
- ExAC rs764433136
- gnomAD rs764433136
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.05
- MetaLR 0.02
- MetaSVM -0.97
- CADD 16.90
- PolyPhen-2 0.02
- SIFT 0.31
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available