Y37C (p.Tyr37Cys) variant of CCR5 (C-C chemokine receptor type 5)
Y37C (p.Tyr37Cys) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
Y37C (p.Tyr37Cys) variant details
- p.Tyr37Cys
- gnomAD 3-46373012-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.485
- REVEL 0.43
- MetaLR 0.33
- MetaSVM -0.22
- CADD 25.90
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available