Y15L (p.Tyr15Leu) variant of CCR5 (C-C chemokine receptor type 5)
Y15L (p.Tyr15Leu) in CCR5 (C-C chemokine receptor type 5) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
Y15L (p.Tyr15Leu) variant details
- p.Tyr15Leu
- rs1559567779
- gnomAD 3-46372945-TA-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.186
- CADD 9.10
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available