Y15I (p.Tyr15Ile) variant of CCR5 (C-C chemokine receptor type 5)
Y15I (p.Tyr15Ile) in CCR5 (C-C chemokine receptor type 5) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
Y15I (p.Tyr15Ile) variant details
- p.Tyr15Ile
- rs758662716
- gnomAD 3-46372943-AT-A
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.283
- CADD 11.20
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available