Y15C (p.Tyr15Cys) variant of CCR5 (C-C chemokine receptor type 5)
Y15C (p.Tyr15Cys) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
Y15C (p.Tyr15Cys) variant details
- p.Tyr15Cys
- ExAC rs777539326
- gnomAD rs777539326
- Missense
- Variant Prioritization Score for Impact Estimate 0.0653
- REVEL 0.05
- CADD 4.75
- PolyPhen-2 0.04
- SIFT 0.16
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available