Y10C (p.Tyr10Cys) variant of CCR5 (C-C chemokine receptor type 5)
Y10C (p.Tyr10Cys) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
Y10C (p.Tyr10Cys) variant details
- p.Tyr10Cys
- gnomAD rs1351407662
- Missense
- Variant Prioritization Score for Impact Estimate 0.361
- REVEL 0.32
- CADD 22.70
- PolyPhen-2 0.83
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available