V5L (p.Val5Leu) variant of CCR5 (C-C chemokine receptor type 5)
V5L (p.Val5Leu) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
V5L (p.Val5Leu) variant details
- p.Val5Leu
- gnomAD 3-46372915-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0746
- REVEL 0.04
- CADD 7.29
- PolyPhen-2 0.00
- SIFT 0.51
- Most common in the Ashkenazi Jewish population (allele frequency 4.1e-05)
- Structural context available
- Literature evidence available