V5E (p.Val5Glu) variant of CCR5 (C-C chemokine receptor type 5)
V5E (p.Val5Glu) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
V5E (p.Val5Glu) variant details
- p.Val5Glu
- gnomAD 3-46372916-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0746
- REVEL 0.05
- CADD 4.50
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available