V46M (p.Val46Met) variant of CCR5 (C-C chemokine receptor type 5)
V46M (p.Val46Met) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
V46M (p.Val46Met) variant details
- p.Val46Met
- cosmic curated COSV10462
- 1000Genomes rs41425744
- ESP rs41425744
- ExAC rs41425744
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.18
- CADD 20.50
- PolyPhen-2 0.73
- SIFT 0.07
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available