V46G (p.Val46Gly) variant of CCR5 (C-C chemokine receptor type 5)
V46G (p.Val46Gly) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
V46G (p.Val46Gly) variant details
- p.Val46Gly
- gnomAD 3-46373039-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.24
- MetaLR 0.26
- MetaSVM -0.40
- CADD 24.30
- PolyPhen-2 0.79
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available