V40M (p.Val40Met) variant of CCR5 (C-C chemokine receptor type 5)
V40M (p.Val40Met) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
V40M (p.Val40Met) variant details
- p.Val40Met
- gnomAD 3-46373020-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- REVEL 0.25
- MetaLR 0.30
- MetaSVM -0.14
- CADD 24.90
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available