S7G (p.Ser7Gly) variant of CCR5 (C-C chemokine receptor type 5)
S7G (p.Ser7Gly) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
S7G (p.Ser7Gly) variant details
- p.Ser7Gly
- gnomAD 3-46372921-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.05
- CADD 15.50
- PolyPhen-2 0.00
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available