S6P (p.Ser6Pro) variant of CCR5 (C-C chemokine receptor type 5)
S6P (p.Ser6Pro) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
S6P (p.Ser6Pro) variant details
- p.Ser6Pro
- TOPMed rs1159424333
- Missense
- Variant Prioritization Score for Impact Estimate 0.0917
- REVEL 0.12
- CADD 0.23
- PolyPhen-2 0.18
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available