S63N (p.Ser63Asn) variant of CCR5 (C-C chemokine receptor type 5)
S63N (p.Ser63Asn) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
S63N (p.Ser63Asn) variant details
- p.Ser63Asn
- gnomAD 3-46373090-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.257
- REVEL 0.15
- MetaLR 0.15
- MetaSVM -0.86
- CADD 16.10
- PolyPhen-2 0.19
- SIFT 0.08
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available