S38L (p.Ser38Leu) variant of CCR5 (C-C chemokine receptor type 5)
S38L (p.Ser38Leu) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
S38L (p.Ser38Leu) variant details
- p.Ser38Leu
- gnomAD rs1443351351
- Missense
- Variant Prioritization Score for Impact Estimate 0.435
- REVEL 0.20
- CADD 22.90
- PolyPhen-2 0.84
- SIFT 0.06
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available