S17W (p.Ser17Trp) variant of CCR5 (C-C chemokine receptor type 5)
S17W (p.Ser17Trp) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
S17W (p.Ser17Trp) variant details
- p.Ser17Trp
- cosmic curated COSV52752
- ESP rs369206494
- ExAC rs369206494
- TOPMed rs369206494
- Missense
- Variant Prioritization Score for Impact Estimate 0.234
- REVEL 0.15
- CADD 19.30
- PolyPhen-2 0.86
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available