S17L (p.Ser17Leu) variant of CCR5 (C-C chemokine receptor type 5)
S17L (p.Ser17Leu) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
S17L (p.Ser17Leu) variant details
- p.Ser17Leu
- cosmic curated COSV99433
- ESP rs369206494
- ExAC rs369206494
- TOPMed rs369206494
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- REVEL 0.14
- CADD 13.60
- PolyPhen-2 0.16
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 5.9e-05)
- Structural context available