R31C (p.Arg31Cys) variant of CCR5 (C-C chemokine receptor type 5)
R31C (p.Arg31Cys) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
R31C (p.Arg31Cys) variant details
- p.Arg31Cys
- TOPMed rs777944058
- gnomAD rs777944058
- Missense
- Variant Prioritization Score for Impact Estimate 0.0856
- REVEL 0.06
- CADD 8.42
- PolyPhen-2 0.34
- SIFT 0.17
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available