Q4K (p.Gln4Lys) variant of CCR5 (C-C chemokine receptor type 5)
Q4K (p.Gln4Lys) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
Q4K (p.Gln4Lys) variant details
- p.Gln4Lys
- gnomAD 3-46372912-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0675
- REVEL 0.05
- CADD 2.36
- PolyPhen-2 0.01
- SIFT 0.85
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available