P35S (p.Pro35Ser) variant of CCR5 (C-C chemokine receptor type 5)
P35S (p.Pro35Ser) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
P35S (p.Pro35Ser) variant details
- p.Pro35Ser
- ExAC rs778497859
- gnomAD rs778497859
- Missense
- Variant Prioritization Score for Impact Estimate 0.334
- REVEL 0.16
- CADD 22.00
- PolyPhen-2 0.56
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available