P35L (p.Pro35Leu) variant of CCR5 (C-C chemokine receptor type 5)
P35L (p.Pro35Leu) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
P35L (p.Pro35Leu) variant details
- p.Pro35Leu
- ExAC rs745372153
- TOPMed rs745372153
- gnomAD rs745372153
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.20
- CADD 16.90
- PolyPhen-2 0.04
- SIFT 0.07
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available