P34S (p.Pro34Ser) variant of CCR5 (C-C chemokine receptor type 5)
P34S (p.Pro34Ser) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
P34S (p.Pro34Ser) variant details
- p.Pro34Ser
- gnomAD 3-46373002-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.524
- REVEL 0.43
- MetaLR 0.27
- MetaSVM -0.44
- CADD 24.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available