M64V (p.Met64Val) variant of CCR5 (C-C chemokine receptor type 5)
M64V (p.Met64Val) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
M64V (p.Met64Val) variant details
- p.Met64Val
- gnomAD 3-46373092-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.134
- REVEL 0.06
- MetaLR 0.06
- MetaSVM -1.08
- CADD 9.39
- PolyPhen-2 0.02
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available