M64L (p.Met64Leu) variant of CCR5 (C-C chemokine receptor type 5)
M64L (p.Met64Leu) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
M64L (p.Met64Leu) variant details
- p.Met64Leu
- gnomAD 3-46373092-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.145
- REVEL 0.07
- MetaLR 0.08
- MetaSVM -1.05
- CADD 11.10
- PolyPhen-2 0.04
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available