M49V (p.Met49Val) variant of CCR5 (C-C chemokine receptor type 5)
M49V (p.Met49Val) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
M49V (p.Met49Val) variant details
- p.Met49Val
- TOPMed rs1450402163
- gnomAD rs1450402163
- Missense
- Variant Prioritization Score for Impact Estimate 0.0501
- REVEL 0.03
- CADD 0.00
- PolyPhen-2 0.01
- SIFT 0.95
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available