M49K (p.Met49Lys) variant of CCR5 (C-C chemokine receptor type 5)
M49K (p.Met49Lys) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
M49K (p.Met49Lys) variant details
- p.Met49Lys
- ExAC rs774482480
- TOPMed rs774482480
- gnomAD rs774482480
- Missense
- Variant Prioritization Score for Impact Estimate 0.203
- REVEL 0.16
- CADD 18.70
- PolyPhen-2 0.14
- SIFT 0.03
- Most common in the East Asian population (allele frequency 0.0001)
- Structural context available