L32P (p.Leu32Pro) variant of CCR5 (C-C chemokine receptor type 5)
L32P (p.Leu32Pro) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
L32P (p.Leu32Pro) variant details
- p.Leu32Pro
- gnomAD 3-46372997-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.517
- REVEL 0.50
- MetaLR 0.31
- MetaSVM -0.28
- CADD 25.60
- PolyPhen-2 0.91
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available