L32F (p.Leu32Phe) variant of CCR5 (C-C chemokine receptor type 5)
L32F (p.Leu32Phe) in CCR5 (C-C chemokine receptor type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
L32F (p.Leu32Phe) variant details
- p.Leu32Phe
- ESP rs374426321
- ExAC rs374426321
- TOPMed rs374426321
- gnomAD rs374426321
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.10
- CADD 7.29
- PolyPhen-2 0.03
- SIFT 1.00
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available